Scientific and Medical Evidence - Listing of Research conducted worldwide section :
Cognitive Dysfunctions & 'Brain Fog'
Serious Brain and nervous system abnormalities .
Scientific Findings in Primer for International Consensus Criteria (2012)
Computerized assessment in neuropsychiatry using CANTAB: discussion paper. Sahakian BJ, Owen AM. J R Soc Med. 1992 Jul; 85(7):399-40
Fray PJ, Robbins TW, Sahakian BJ. Neuropsychiatric applications of CANTAB. Int J Geriat Psychiat. 1996;11:329–336. doi: 10.1002/(SICI)1099-1166(199604)11:4<329::AID-GPS453>3.3.CO;2-Y. [Cross Ref] [Reference List]
CFI information -  http://www.umdnj.edu/cfsweb/CFS/cfshome.html

Tests

• Dr. Byron Hyde one of the top ME doctors in the world recommends several cognitive tests for ME
  
  
  • Cognitive and Neurological Tests

• Cambridge Neuropsychological Test Automated Battery (CANTAB) is currently the most practical single tool to assess cognition in ME research studies

• Rozelle Test Battery (RTB)

• Cognitive Function Index

• Strauss E, Sherman EMS, Spreen O. A compendium of neuropsychological tests. 3rd ed.New York: Oxford University Press (2006).

• Lezak MD, Howieson DB, Loring DW. Neuropsychological assessment. 4th ed. New York: Oxford University Press (2004).

• Wechsler D. Wechsler adult intelligence scale-revised. San Antonio, Texas: The Psychological Corporation (1981).

• BOLD fMRI scans. Objective evidence of cognitive complaints in Chronic FatigueSyndrome: A BOLD fMRI study of verbal working memory
  Tanaka M et al, “Reduced Responsiveness is an Essential Feature of Chronic Fatigue Syndrome: a fMRI Study,” BMC Neurol Feb 22; 6 (2006): 9.
  Yoshiuchi K, “Patients with Chronic Fatigue Syndrome have Reduced Absolute Cortical Blood Flow.” Clin Physiol Funct Imaging Mar 26(2) (2006): 83-6.
  Lange G et al, "Objective Evidence of Cognitive Complaints in Chronic Fatigue Syndrome: a BOLD fMRI Study of Verbal Working Memory," Neuroimage Jun 26(2) (2005):5 13-24.
  De Lange FP et al, "Gray Matter Volume Reduction in the Chronic Fatigue Syndrome," Neuroimage Jul 1; 26(3)(2005): 777-81.

• The following tests may explain cognitive deficits
  
  
  • Neurological Inflammation
  
  
  • Brain Scans - hypo-perfusion and lesions on the brain, EEG spectral coherence, NMDA activity
  
  
  • Infections  -  main cause of immune system abnormalities in patients (Found in high percentage of CFS cases)
    (a) Test for Viruses, Chalmydia, Mycoplasmas, Babesia and Brucella
    (b) Test for Chronic Rickettsia
    (c) Test for Chronic Lyme disease
    (d) Multiple Infections
  
  
  • Hypoglycemia Test