Scientific and Medical Evidence - Listing of Research conducted worldwide section :
Abnormal glandular functions & Abnormal HPA axis (Hypothalmus Pituary Adrenal axis)
Increased oxidative stress
Inability to metabolise glucose and sugar .
Canadian Criteria 2003 http://www.me-ireland.com/canada-overview.pdf

Some clinical studies and research studies show that many ME patients have Hypoglycemia. This can worsen fatigue and lead to mood disorders, anxiety, brain fog and weakness. Dr. Edward Conley of the Fatigue, Fibromyalgia and Autoimmune Clinic, Michigan, USA has found that many of his ME patients have hypoglycemia. Though some ME patients have been found to have diabetes after intensive tests.

• Ask your doctor or medical specialist or endocrinologist to run Hypoglycema tests and Diabetes tests. These tests are run over the course of 24 hours or 48 hours and provide detailed measurements and analysis of blood sugar levels and fluctuations over time. These tests are very important for ME / CFS patients.

• Short chain fatty acids test

• The Endocrine system is affected by severe blood sugar fluctuations, in particular Hypoglycemia and Diabetes. Get HPA axis and Thyroid and Adrenal glands dysfunction tests (Found in high percentage of CFS cases)